Aging population and an increasing number of cancer patients signifies a steady increase in patients undergoing advanced operations. The identified user need is an improved postoperative monitoring in gastrointestinal surgery. Our survey and interviews among health care professionals identified the need of monitoring the anastomosis after bowel and oesophagus surgery as the field with the most immediate need for rapid postoperative monitoring.

In the oesophagus case the patients are often quite sick and have a high mortality rate due to the seriousness of the cancer. The need for monitoring these patients is high in order to avoid further complications and enhance the well-being and decrease mortality rate. Senzime’s solution can be very beneficial in comparison to current methods in the oesophagus case. Rapid methods to determine complications after colorectal surgery are also missing and e.g. a serious condition is leakage in the anastomosis, that may develop into peritonitis (inflammation of the peritoneum) and sepsis. This can be prohibited before it becomes critical by detection of changes in biomarker concentration indicating insufficient oxygenation (ischemia) in the wound.

None of the existing techniques are sufficiently sensitive or specific enough to efficiently detect the status of the target organ. Deteriorating conditions can proceed undetected placing the patient at high risk, delaying diagnosis, make treatment more demanding, higher health care cost and death.