The CliniSenz Analyzer is based on the patented biosensor technology that provides highly accurate and highly specific determinations of biomarkers such as glucose- and lactate trends.
CliniSenz Analyzer consist of a sensor that is a microfluidic chip containing tiny moulded micro channels, with a micro reactor in the centre. The micro reactor, which is the “heart” of the biosensor, contains a support material made of high-grade, porous micro spheres onto which highly specific enzymes are bound. To achieve maximum sensitivity, the channels are designed and laid out in a special pattern that enables nearly full enzymatic conversion rate and rapid response time.
Altogether, the specially designed reactor in combination with the effective fluid pattern creates a highly accurate sensor chip. The sensor chip used in the CliniSenz Analyzer is based on heat flux sensor technology which is a technique that provides highly accurate and highly specific determinations of a substance without interference from other substances. This is made possible by the fact that the biosensor only detects the heat flow from the enzymatic reaction. This technique is very different from other sensor technologies that is dependent on effects from electron transport, light emittance, fluorescence or such. In clinical practice as well as pharmaceutical industry, interference with other substances can introduce significant limitations.
Patients, for instance, may have different levels of potentially interfering substances in the blood, and they may also receive medications that can alter plasma glucose values. Examples of some common substances that interfere with accurate measurement of plasma glucose levels are paracetamol, ascorbic acid, uric acid, dopamine, acetylsalicylic acid, maltose and various sugar alcohols.